On expression of VEGF-C and its receptor in breast carcinoma tissue and in peritumoral tissue and their clinic significance
- VernacularTitle:乳腺癌及癌周组织中淋巴内皮生长因子及其受体的表达和意义
- Author:
Xiao-Jun MA
;
Yong-Dong PU
;
Jian-Miao HE
;
Liang-Hong NI
;
Hong-Xing JIA
;
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Vascular endothelial growth factor C;
Vascular endothelial growth factor receptor-3;
Lymphangiogenesis;
Lymphatic metastasis
- From:
Cancer Research and Clinic
1997;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of VEGF-C and its receptor in breast carcinoma tissue and in peritumoral tissue,as well as their clinic significance.Methods Immunohistochemistry SP method was used to examine the expression of VEGF-C and VEGFR3 in 70 cases of breast cancer and in its peritu- moral tissue.Results In all 70 cases of breast cancer,the positive expression rate of VEGF-C in breast car- cinoma tissue was 78.6 %,and its rate in peritumoral tissue was 54.3 %.There was a significant stastistic dif- ference between the two groups(P
