Effect of levetiracetam as an add-on to partial seizure on cognitive function and quality of life
- VernacularTitle:左乙拉西坦添加治疗对部分性癫癎患者认知功能及生活质量的研究
- Author:
Bo ZHOU
;
Dong ZHOU
;
Lin-Yu TIAN
;
Zhen HONG
;
Jun XIAO
;
- Publication Type:Journal Article
- Keywords:
Epilepsies,partial;
Anticonvulsants;
Piracetam;
Randomized controlled trials;
Cognition;
Quality of life
- From:
Chinese Journal of Neurology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of levetiracetam(LEV)on cognitive function and quality of life of patients with partial seizure.Methods There were two phase for this study.Phase one was a randomized,double-blind,placebo-controlled study for 16 weeks.Phase two was an open label period for 24 weeks.Medicated patients underwent test on the cognitive function and Health Related Quality of Life (HRQOL)at the baseline respectively at the end of 16 weeks and at the end of 40 weeks.Results(1) Compared the result at the end of 16 weeks with the baseline,LEV group used less time to do Wisconsin card sorting test(WCST,reduce scores -110.3),delayed logical memory were improved(reduce scores 3.4,P
