Transsphenoidal microsurgical treatment of male prolactinoma and sexual disfuction
- VernacularTitle:经蝶显微手术治疗男性泌乳素腺瘤及对性功能的影响
- Author:
Dong-Sheng HE
;
Hai-Jun WANG
;
Lei FENG
;
Chao YANG
;
- Publication Type:Journal Article
- Keywords:
Prolactinoma;
Transsphenoidal approach;
Microsurgical operation;
Male
- From:
Chinese Journal of Microsurgery
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the features of transsphenoidal microsurgical treatment of male pro- lactinoma and to evaluate the sexual function before and after transsphenoidal microsurgery.Methods A se- ries of 23 cases male prolactinoma were analysed combined with retrospective and prospective study.9 casese with sexual disfunction had finished the International Index of Erectile Function with 15-item questionnnaire (ⅡEF-15) before and after the surgery.Results 8/10 cases treated with dopaminergic agonist combined with surgery achieved complete remission,while only 4/13 cases achieved complete remission with surgery on- ly(x~2=5.490,P=0.036).Aecoding toⅡEF-15,sexual function improved after surgery in 9 cases(paired- sample) t test,P＜0.05).Conclusion Transsphenoidal microsurgical treatment of prolactinoma may im- prove the male sexual functions.Dopaminergic agonist combined transsphenoidal microsurgery may achieve a better outcome.
