Gene expression profiling of skeletal muscle in type 2 diabetic rats
- VernacularTitle:2型糖尿病大鼠骨骼肌基因表达谱研究
- Author:
Jun-Ping WEN
;
Li-Xiang LIN
;
Gang CHEN
;
Wei-Te ZHUANG
;
Lian-Tao LI
;
Miao LIN
;
Qing-Ming LIN
;
- Publication Type:Journal Article
- Keywords:
Insulin resistance;
Diabetes mellitus,type 2;
Rats,Sprague-Dawley;
Gene expression;
Oligonucleotide array sequence analysis
- From:
Chinese Journal of Endocrinology and Metabolism
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Differences in gene expressions were compared by cDNA microarray in skeletal muscle of type 2 diabetic rats and normal rats.In diabetic rats,157 genes were down-regulated and 100 genes up-regulated. Some of these genes were related to insulin resistance,glucose and lipid metabolism.
