A study on the correlation between FHIT protein and cPKC? expression and invasion and metastasis in non-small cell lung cancer
- VernacularTitle:脆性组氨酸三聚体蛋白和蛋白激酶C?的表达及其与非小细胞肺癌侵袭、转移的相关性
- Author:
Penghui ZHUANG
;
Jingren LIANG
;
Cheng'En PAN
;
Junke FU
;
Dong SHANG
;
- Publication Type:Journal Article
- Keywords:
NSCLC;
FHIT;
cPKC?;
invasion;
immunohistochemistry
- From:Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of FHIT protein and cPKC? in invasion and metastasis in non-small cell lung cancer(NSCLC).Methods The expression of FHIT protein and cPKC? in 41 specimens of NSCLC and 11 cases benign lung tissues were examined by immunohistochemical technique.Results The positive rate of FHIT protein and cPKC? in NSCLC tissues were 48.8% and 53.7% respectively.The positive rate of FHIT protein and cPKC? in benign lung tissues were 90.9% and 18.2% respectively.They were significantly different(P
