Expressions of glucose transporter 1 and 3 proteins are changing with blood glucose concentration in diabetic rat brain
- VernacularTitle:糖尿病大鼠脑葡萄糖转运子1和3蛋白表达随血糖浓度而变化
- Author:
Yu-Xin XIAN
;
Wei-Kai HOU
;
Xin-Guo HOU
;
Ming DONG
;
Li CHEN
;
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Monosaccharide transport protein;
Immunohistochemistry
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Streptozotocin-induced diabetic model was prepared in Wistar rats and the blood glucose levels were controlled at 3 levels of＜10,10-14 mmol/L or＞16.7 mmol/L by insulin,and changes of glucose transporter(GLUT)1 and 3 protein expressions of brain were observed in control rats and diabetic rats with different blood glucose levels by immunohistochemistry.The results showed that chronic hyperglycemia could decrease the protein expressions of GLUT 1 and GLUT3.
