Changes of gene expressions of adiponectin in adipose tissue and adiponectin receptor R1 in skeletal muscle of type 2 diabetic rats
- VernacularTitle:2型糖尿病大鼠脂肪组织脂联素和骨骼肌组织脂联素受体R1基因表达的变化
- Author:
Hui YAO
;
Han-Hua LIN
;
Hong-Wei WANG
;
Long-Jiang ZHANG
;
Xiao-Yan HUANG
;
Zhi XIA
;
- Publication Type:Journal Article
- Keywords:
Adiponectin;
Adiponectin receptors;
Diabetes mellitus,type 2;
Rosiglitazone
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The mRNA levels of adiponectin in adipose tissue and adiponectin receptor R1 in skeletal muscle of type 2 diabetic rats were examined by semi-quatitative RT-PCR.The expression of adiponectin receptor R1 was not altered in the skeletal muscle of type 2 diabetic rats as compared with normal rats.The serum adiponectin level was decreased in diabetic rats due to the decline of adiponectin mRNA level in adipose tissue and rosiglitazone improved the adiponectin deficiency.
