The role of complement activation in the pathogenesis of diabetic complications
- VernacularTitle:糖尿病并发症发病过程中的补体活化作用
- Author:
Ming-Cai QIU
;
Chun-Mei MENG
;
- Publication Type:Journal Article
- Keywords:
C5b-9;
Diabetic nephropathy;
Diabetic retinopathy;
Diabetic neuropathy
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Complement system is an important constituent in immune system.Membrane attack complex (C5b-9)is the final ingredient in the complement activation.Recently,a few studies showed that C5b-9 deposition was found in the diabetics with chronic complications,indicating that complement activation might be involved in the pathogenesis of diabetic complications.Our aim is to summarize some newly published works and show a prelimimary work we did in this area.We hope that more attention should be paid to the role of autoimmune mechanism in diabetic complications.
