Experimental study on diagnosing the brachial plexus injury through quickly detecting the ChAT activity
- VernacularTitle:胆碱乙酰基转移酶活性快速测定诊断臂丛损伤的实验研究
- Author:
Zhi-Fu LI
;
Yang-Bin XU
;
Chang-Zheng LIU
;
- Publication Type:Journal Article
- Keywords:
Brachial plexus;
Choline acetyltransferase;
Radioisotope
- From:
Chinese Journal of Microsurgery
2000;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore a better method to diagnose the brachial plexus injury as pre-or post-ganglionic,which is quick,simple,quantitative,cheap and accurate.Methods Forty-five SD rats were divided randomly ino pre-or post-ganglionic brachial plexus injury models group,and the choline acetyl- transferase(CHAT)activity was detected by using the radioisotope after different days.Results The ChAT activity of two groups both fall day by day:in the pre-agnglionic group,it falls quickly,and reach 1/10 of nor- mal(675?258)cpm;in the post-ganglionic group,it falls slowly,and reach 1/2 of normal even after 90 days (4906?1119)cpm.Conclusion Intra-operative measure of ChAT can be used to differentiate pre-or post- ganglionic brachial plexus injury.
