Influence of anti-depression therapy on cardiac function and short-term prognosis in elderly patients with congestive heart failure
- VernacularTitle:抗抑郁治疗对伴抑郁症状的慢性心力衰竭患者心功能及近期预后的影响
- Author:
Xiang-Qun LIU
;
Hong-Yong TAN
;
Pei-Yan SHAN
;
Xian-Lin GAO
;
Ming-Peng ZHANG
;
Jin-Zhong LIU
;
- Publication Type:Journal Article
- Keywords:
Heart failure,congestive;
Depression;
Fluoxetine
- From:
Chinese Journal of Geriatrics
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of anti-depression therapy on cardiac function and short-term prognosis in elderly patients with congestive heart failure (CHF) and the safety and effectiveness of fluoxetine in these patients.Methods Ninety six elderly hospitalized patients with CHF accompanied with depressive disorder were randomly divided into two groups:fluoxetine (20mg once daily)and placebo treated groups based on the routine cardiac drug therapy for 3 months. Results The prevalence rate of depressive disorder in elderly patients with CHF was 31.1%.The length of stay of fluoxetine group was shorter than that of placebo group.The post-treatment depressive exponents of self-rating depression scale(SDS)in fluoxetine group (51.39%?8.63)was lower than those in pretreatment and in placebo group.The improvement of cardiac function in fluoxetine group(53.4%?4.5%) was much better than that of placebo group (P
