Time-dependent changes of astrocytes and CD31-marked microvessels in human cerebral infarction
- VernacularTitle:人脑梗死后星形胶质细胞反应和微血管标记物相关性的研究
- Author:
De-Sheng WANG
;
Ji-Ping QI
;
Guang-Wei LI
;
He WU
;
Dan-Dan WANG
;
- Publication Type:Journal Article
- Keywords:
Brain ischemia;
Astrocytes;
Blood vessels;
Microcirculation
- From:
Chinese Journal of Geriatrics
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the time-dependent changes of astrocytes and microvessels in the ischemic core and surrounding areas.Methods Glial fibrillary acidic protein (GFAP)was measured by HE,and CD31 by immunohistochemistry as markers in post-mortem specimens from ten patients,who died of cerebral infarction.Results Each section of the infarcted brains was divided into four areas (the area 0-3).GFAP expressed a little in area 0 and 1,increased in a time-dependent manner in area 2 and 3;CD31 die not expressed in area 0,expressed a little in the area 1,and increased in area 2 and 3 continuously.Conclusions The proliferation of astrocytes and microvessels may play a significant role in the process of restoration after cerebral infarction.
