Liver transplantation for viral hepatitis and hepatic cancer
- VernacularTitle:病毒性肝炎、肝癌与肝移植
- Author:
Cheng'En PAN
;
- Publication Type:Journal Article
- Keywords:
liver transplantation;
viral hepatitis;
hepatocellular carcinoma;
fulminant hepatic failure
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Orthotopic liver transplantation(OLT) has been performed for 42 years.Survival rates have climbed to as high as 88% at 1-year and operative mortality rates have dropped to as low as 0%.Liver resection should still be considered the first-line treatment for patients with hepatocellular carcinoma(HCC) in non-cirrhotic and resectable livers.Liver transplantation must be the preferred approach for cirrhotic livers.OLT for HCC at a more advanced stage is not indicated.Combination therapy with hepatitis B immune globulin(HBIG) and lamivudine for hepatitis B virus(HBV) patients before and after OLT has been reported a survival benefit as compared to non-HBV recipients.Liver transplantation should not be advocated at the hospitals without primary working conditions.