Changes of gastric emptying after acute myocardial infarction in awake rats
- VernacularTitle:急性心肌梗死大鼠胃排空的变化
- Author:
Shi-Xiong LIU
;
Xiang YAN
;
Shao-Li SONG
;
Li ZHAO
;
Peng YANG
;
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Gastric emptying;
Motilin
- From:
Chinese Journal of Geriatrics
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of gastric emptying in awake rats after acute myocardial infarction(AMI). Methods The male Wistar rats were submitted to thoracotomy followed by or not by occlusion of the left coronary artery. After 24 h, AMI(n=12)and sham groups (n=9)were fed in gavage(1 ml)with ~(99m)-Tc-DTPA labeled test meal. Half gastric emptying time (GET1/2) and 50min residual rate were measured by single photon emission computed tomography. The rats of AMI group were sacrificed after 50 min. Plasma level of motilin was measured by radioimmunoassay in AMI and sham group respectively(n=9). Results GET1/2 was significantly higher in AMI group[(23.1?4.7)min] than in sham group[(16.0?4.0)min](P
