The immunological features and clinical values of plasma autoantibodies to A? in elderly patients with Alzheimer's disease
- VernacularTitle:阿尔茨海默病患者自身抗?淀粉样蛋白抗体的免疫特性和临床价值
- Author:
Wu-Hua XU
;
Shoji MIKIO
;
Matsubara ETSURO
;
- Publication Type:Journal Article
- Keywords:
Alzheimer disease;
Autoantibodies;
Amyloid beta-protein
- From:
Chinese Journal of Geriatrics
1995;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05),and no significant relationship were observed between the A? autoantibody and the severity of dementia or the natural course.TAPIR positive plasma showed a stronger immunoaffinity with monomeric and dimeric A?40 and FA? than with monomeric A?42,but a weak immunoaffinity with dimeric A?42.Conclusions Naturally existing plasma antibodies to A? might not be an useful biomarker for AD diagnosis,and could not affect clinical signs and natural progress of AD.
