No relationship between single nucleotide polymorphisms of vitamin D receptor gene and bone mass in Tibetan women
- VernacularTitle:藏族妇女维生素D受体基因BsmⅠ多态性与骨量无关
- Author:
Qi WANG
;
Baofeng GE
;
Ying YIN
;
Menghai BAI
- Publication Type:Journal Article
- Keywords:
Receptor, calcitriol;
Polymorphisms, single nucleotide;
Osteoporosis;
Quantitative ultrasonography
- From:
Chinese Journal of Endocrinology and Metabolism
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The single nucleotide polymorphisms (SNP) of vitamin D receptor (VDR) gene were determined by BsmI restriction endonuclease analysis and quantitative ultrasonography indexes (QUI) of calcaneum were measured in Tibetan women. The results showed that there were no statistical differences between QUI of different genetypes and between distribution frequencies of gene types in young women and menopausal women. And it was found that the SNP of VDR by BsmI restriction endonuclease analysis was not relevant to bone mass acquisition and rate of bone mass loss.
