Pro12Ala variant in PPAR?-2 gene is associated with overweight and obesity in Chinese population
- VernacularTitle:PPAR?-2基因Pro12Ala多态性与中国人超重和肥胖相关
- Author:
Jin LU
;
Dajin ZOU
;
Guangchun CHEN
;
Jian LU
- Publication Type:Journal Article
- Keywords:
Obesity;
Peroxisome proliferator activator receptor-?;
Polymorphism, restriction fragment length
- From:
Chinese Journal of Endocrinology and Metabolism
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The genotypes of PPAR? 2 gene were determined by PCR RFLP in 232 Chinese individuals. In obese group (130 cases), “Ala” allele was associated with increased body mass index (BMI), hip circumference and serum uric acid level, and this gene polymorphism was independently associated with BMI, suggesting that this gene polymorphism is associated with overweight and obesity in Chinese population.
