Effects of Formaldehyde Escaped From Plywood Exposure on Neurotransmitter in the Brain of Mice
- VernacularTitle:胶合板释放物甲醛对小鼠脑组织神经递质的影响
- Author:
Yong-Ling XIE
;
Ke-Ming LIU
;
Ming-Yue ZHANG
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Formaldehyde Neurotransmitter Plywood panels
- From:
Journal of Environment and Health
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of repeated exposure by inhalation to several concentrations of formaldehyde 5 hours/day 7 consecutive days on the content of neurotransmitters in the brain of adult female BALB/c mouse. Methods The 24 mice were randomly divided into 3 groups(groups A to C) 8 in each and exposed respectively to formaldehyde of 0.02-0.07 mg/m3 controls 0.99-1.2 mg/m3(3 m2 plywood/m3 room)and 3.44-3.63 mg/m3(10 m2 plywood/m3 room). After sacrifice the brain were excised and the neurotransmitters were examined. Results Asp、NE、Glu、E and Ach in animals of the exposed groups were significantly decreased but GABA was increased. Conclusion Exposure of formaldehyde escaped from plywood may result in neurochemical change such as Asp NE GluE Ach and GABA in the brain of mouse.
