Effects of Airborne Particles on Micronuclear Frequency of Human Binucleate Lymphocytes
- VernacularTitle:大气颗粒物对人双核淋巴细胞微核率的影响
- Author:
Fu-Sheng YUAN
;
Ya-Ping MA
;
Wu-Hong ZHAO
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Particles matteer Binucleate lymphocytes Micronucleus test
- From:
Journal of Environment and Health
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of airborne particles exposure on the micronucleus frequency of human binucleate lymphocytes. Methods Airborne particles were collected at a residential area of Taiyuan city with classification air samplers.The organic substance was extracted by dichloromethane acetone and methanol in a Soxhlet apparatus. Four metals,Ni Pb Cd and Cr in airborne particles were extracted by 1∶1 nitric acid and determined by atomic absorption spectrophotometry.The mutagenicity of the extracts of airborne particles was studied with cytokinesis-locking assay. Results The content of airborne particles in the area was 0.791 9 mg/m3exceeded the related standard by 4.28 times. The small particles contained more metals elements and organic substances than the big particles. The extracts of airborne particles induced a significant increase in micronucleus production P
