Expression and significance of matrix metalloproteinases2 and tissue inhibitors of metalloproteinases2 in renal clear cell carcinoma
- VernacularTitle:MMP2、TIMP2在人肾透明细胞癌中的表达及意义
- Author:
Wei TANG
;
Keijiro TAKASHI YAO
;
KIYOSHIMA
;
Al ET
- Publication Type:Journal Article
- Keywords:
Renal clear cell Carcinoma;
MMP2;
TIMP2
- From:
Chinese Journal of Urology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Conclusions MMP2 expression is positively correlated with the grade and stage of renal cancer, indicating that increased expression of MMP2 protein in RCCC is associated with poor prognosis of RCCC.By contrast,the abnormal expression of TIMP2 and its function of inhibiting tumor infiltration and migration need further investigation.MMP2 can be used as a useful molecular marker for prognosis of RCCC.
