Serum remnant-like particle cholesterol concentration and its clinical significance in the patients with type 2 diabetes mellitus
- VernacularTitle:2型糖尿病患者血清残粒样微粒胆固醇水平及其临床意义
- Author:
Xingliang JIANG
;
Jingguo ZHOU
;
Zhong TANG
;
Jun ZHANG
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus, type 2;
Remnant-like particle-cholesterol;
Diabetic nephropathies;
P-selectin (GMP 140);
Nitric oxide
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the change of serum remnant like particle cholesterol (RLP C) and the association of RLP C with diabetic nephropathy (DN) in the patients with type 2 diabetes mellitus (DM). Methods Serum RLP C concentration was assayed by immunoseparation method. Plasma ? granule membrane glycoprotein 140 (GMP140) and nitric oxide (NO) levels were also measured. Urinary albumin excretion rate (UAER) was measured by radioimmunoassay, and the patients with type 2 DM were assigned to three groups according to UAER 〔35 without DN (D 1 group, UAER200 ?g/min)〕. Results Serum RLP C concentration in 96 patients with type 2 DM was significantly increased compared to that in 44 normal controls (NC) 〔(0.281?0.162)mmol/L vs (0.193?0.125)mmol/L, P
