The role of nitric oxide in the pathogenesis of type 2 diabetes mellitus
- VernacularTitle:一氧化氮在2型糖尿病发病机制中的作用
- Author:
Chunhong SONG
;
Ruifeng LI
;
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus, type 2;
Nitric oxide;
Insulin resistance
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Under pathologic conditions, nitric oxide causes peripheral insulin resistance by impairing key signal molecules of insulin signaling pathway and mediates dysfunction of islet ? cells caused by lipids, cytokines and hyperglycemia, which plays an important role in the pathogenesis of type 2 diabetes mellitus.
