Olfactory function in patients with Parkinsons disease
- VernacularTitle:帕金森病患者的嗅觉改变
- Author:
Liyan ZHANG
;
Piu CHAN
;
- Publication Type:Journal Article
- Keywords:
Parkinson disease;
Smell;
Diagnosis
- From:
Chinese Journal of Neurology
1999;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the olfactory function in Chinese patients with Parkinsons disease (PD) and its application in diagnosis and differential diagnosis of Parkinsonism Methods The thresholds of olfactory detection and identification were determined by using “five odors olfactory detection arrays” provided by Chinese Academy of Sciences for the 50 PD patients, 30 healthy controls, 30 persons with other neurological diseases, and 7 atypical Parkinsons disease patients Results The olfactory detection and identification thresholds of PD patients were significantly higher than those of the normal controls and than those with other neurological diseases But the olfactory identification threshold of PD patients was significantly higher than those with atypical Parkinsons disease The sensitivity and specificity in the olfactory test were 74 0% and 91 7%, respectively by combining the olfactory detection and identification thresholds together Conclusions The olfactory function was found significantly decreased in PD patients The olfactory test might play an important role in the diagnosis and differentiated diagnosis of PD
