Effects of E-selectin and ligand on adhesion and implantation of embryo
- VernacularTitle:E-选择素及其配体sLe~x对胚泡粘附和着床的影响
- Author:
Wei ZHANG
;
Jianping ZHOU
;
Jin ZHU
;
Yinkun LIU
- Publication Type:Journal Article
- Keywords:
E seletin;
sLe x;
Blastocyst;
Attachment;
Implantation
- From:
Chinese Journal of Immunology
1999;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study effects of E selectin and ligand on adhesion and implantation of embryo.Methods:The mouse hatched blastocysts were cultured in vitro and the effects of E selectin and anti sLe x on the attachment of embryos were observed. The implantation rates of embryos were observed after anti sLe x at differential concentrations was injected to uterine cavity of mouse from pregnant day 2 to day 4.Results:The attachment rate of embryos (88 0%、87 2%) at concentrations of 25 ng/ml and 50 ng/ml E selectin was significantly higher than control group (74 0%) ( P
