A clinical investigation of AmpC ? lactamases producing enterobacteriaceae strains in senil infectious patients
- VernacularTitle:老年感染性疾病患者中肠杆菌科细菌产AmpC?-内酰胺酶菌株的临床分析
- Author:
Shaohua PNEG
;
Yu ZHAN
;
Congrong LI
;
Jingling SHI
;
- Publication Type:Journal Article
- Keywords:
Enterobacteriaceae infections;
Drug resistance, microbial
- From:
Chinese Journal of Geriatrics
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the infection condition of AmpC ? lactamases producing strains for reasonable use of antibiotics in clinic. Methods Adopting modified three dimensional extract test was adopted to detect enterobacteriaceae strains, and 12 antibiotics were determined by the antimicrobial disk diffusion susceptibility tests in specimen collected from 233 senile infectious patients. Results The total isolating rate of AmpC ? lactamases producing enterobacteriaceae strains in senile patients was 8 6%. The incidence of AmpC ? lactamases producing strains was found most often in E.cloacae. The AmpC ? lactamases producing strains were susceptive to imipenem and there the resistance rates to imipenem were 100 0%. The resistance rates to cefepime were 85%～100% to the third generation cephalosporins and aztreonam Conclusions The drug resistance of AmpC ? lactamases producing enterobacteriaceae is very serious. It is important to surveillance and control drug resistance of AmpC producing strains.
