The relationship between TNF-? and chronic otitis media
- VernacularTitle:肿瘤坏死因子和慢性中耳炎的关系
- Author:
Bin SUN
;
Gang CHEN
;
Min XU
;
Quan'An ZHANG
;
- Publication Type:Journal Article
- Keywords:
otitis media;
cholesteatoma;
granulation tissue;
TNF-?
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the expression and localiz at ion of tumor necrosis factor alpha (TNF-?) of granulation tissue and chole steatoma in chronic otitis media, and explore its relationship with chronic otit is media. Methods The expression of TNF-? was observe d by immunohistochemical method in cholesteatoma, granulation tissue and normal external ear canal skin in 42 cases with chronic otitis media. Results The level of TNF-? in the group of the sample s including cholesteatoma and granulation tissue increased significantly (P