Diagnostic value of CYFRA21-1,NSE,CA15-3,CA19-9 and CA125 assay in pleural effusions in elderly patients
- VernacularTitle:血清和胸水中肿瘤标志物检测对老年人胸腔积液的诊断价值
- Author:
Changsheng LI
;
Bangchang CHENG
;
Wei GE
;
Jiangfei GAO
;
- Publication Type:Journal Article
- Keywords:
Tumor markers, biological;
Pleural effusion
- From:
Chinese Journal of Geriatrics
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim of this study was to evaluate the individual and combined diagnostic value of five tumor markers in the elderly patients with pleural effusion. Methods Serum and pleural levels of cytokeratin fragment19(CYFRA21 1), neuron specific enalase(NSE), carbohydrate antigen15 3(CA15 3), carbohydrate antigen19 9(CA19 9) and carbohydrate antigen 125(CA125) were assayed in 32 elderly patients with malignant pleural effusions resulting from advanced lung cancer and in 30 elderly patients with benign pleural effusions by ELISA. Results Serum levels of CYFRA21 1, NSE, CA15 3, CA19 9 and CA125 in patients with malignant pleural effusions were (12 84?6 48) ?g/L, (22 07?11 25) ?g/L, (65 74?30 26) kU/L, (56 32?25 67)kU/L and (71 86?31 45) kU/L, respectively and were significantly higher than those patients with benign pleural effusions (P
