Prevention and Treatment for Recurrence of Hepatitis B after Liver Transplantation
- VernacularTitle:肝移植术后乙肝复发的预防和治疗
- Author:
Chunman LI
;
Li LI
;
- Publication Type:Journal Article
- Keywords:
Liver transplantation Hepatitis B Immunoglobulin Interferon Famcyclovir Lamivudine
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevention and treatment for recurrence of hepatitis B after liver transplantation on HBV related diseases.Methods Making a literature summarization based on published papers review.Results Acute and chronic HBV related diseases are the main indications of liver transplantation.Recurrence rate of hepatitis B is from 80% to 100% in the untreated patients after liver transplantation,and it affects the survivals of patients seriously.It has become a focus to prevent and treat the recurrence of hepatitis B.After a series of explotation and application,there have been a lot of drugs of preventing and treating HBV reinfection, including hepatitis B immunoglobulin,interferon and nucleotide analog antivirus drugs(lamivudine, famcyclovir, adefovir),etc.The therapeutic characteristics of them are different. Their utilizations of dividing or alliance are developing rapidly Conclusion Liver transplatation is an effective therapy for HBV related disease. Anti HBV treatments perioperation play an important role in the improvement of succeed of liver transplantation.
