Inflammatory Pathogenesis in Pancreatic Cancer Development and Its Therapy Strategy
- VernacularTitle:胰腺癌发生的炎症机理及治疗策略
- Author:
Hu ZHANG
;
Xubao LIU
;
- Publication Type:Journal Article
- Keywords:
Pancreatic cancer Inflammatory pathogenesis Therapy
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the development of pancreatic cancer and inflammation, and the therapy strategy.Methods Related articles were reviewed.Results The pathogenesis of inflammation in pancreatic cancer development involves cytokines, NF ?B, COX 2, PPAR ?, DNA damage, gene changes,etc. Based on these mechanisms some medications are under developing.Conclusion Accumulative effects of pancreatic inflammation may lead to DNA changes, and even pancreatic cancer development. Medications aimed at suppressing pancreatic inflammation may help with prevention and treatment of pancreatic cancer.
