Mouse Bone Marrow Cell Mutation Induced by Vechile Exhaust
- VernacularTitle:汽车尾气对小鼠骨髓细胞的致突变性
- Author:
Changjiang REN
;
Yan LUO
;
Hongwei WANG
;
- Publication Type:Journal Article
- Keywords:
Vechile exhaust;
Mutation;
Micronucleus test;
Sister chromatid exchange, test
- From:
Journal of Environment and Health
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of the mouse bone marrow cell mutation induced by vechile exhaust. Methods The mice were divided into two groups. The experimental group exposed to car exhaust, after exposure of given days (15 d, 30 d, 45 d, 60 d), bone marrow micronucleus and SCE rates in the experimental group were compared with the control. Results Significant differences had been seen between the two groups in bone marrow micronucleus and SCE rates except the 15 d group. The rate of the bone marrow cell mutation was positively correlated to the periods of exposure to car exhaust. Conclusion Car exhaust has effect of mutation on mouse cells.