Control study of regional cerebral blood flow in both effective treated and incomplete controlled patients of idiopathic generalized tonic clonic seizure
- VernacularTitle:有效控制与控制不良的特发性全面性强直阵挛发作癫癎患者局部脑血流的对照研究
- Author:
Kai-Yan WANG
;
Chuan-Zhen LV
;
Zhen HONG
;
Xing-Dang LIU
;
Min HOU
;
- Publication Type:Journal Article
- Keywords:
Epilepsy,tonic-clonic;
Brain;
Regional blood flow
- From:
Chinese Journal of Neurology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore sub-clinical items in evaluating the prognosis of epileptic patients,the study on differences of regional cerebral blood flow (rCBF) in both effective treated and incomplete-controlled patients with idiopathic generalized tonic clonic seizure (GTCS) was carried out.Methods Interictal rCBF measurements using 99m Tc-ethyl cysteinates dimmer (ECD) SPECT was performed on 29 effective treated idiopathic GTCS patients and 12 incomplete controlled idiopathic GTCS patients. The rCBF distribution was semi-quantitatively analyzed by regions of interest (ROIs) comparing with abnormal rate of interictal hypoperfusion rCBF,clinical seizure time and EEG.Results ROI analysis showed that rCBF decreased in basal ganglia and thalamus of incomplete controlled patients with idiopathic GTCS compared to that of effective treated ones′ significantly ( P
