Analysis of the risk factors and drug sensitive tests of lower respiratory tract infection by stenotrophomonas maltophilia in the elderly
- VernacularTitle:老年人下呼吸道嗜麦芽窄食单胞菌感染的临床分析
- Author:
Junguang JIANG
;
- Publication Type:Journal Article
- Keywords:
Stenotrophomonas maltophilia;
Respiratory tract infections;
Drug resistance, microbial
- From:
Chinese Journal of Geriatrics
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse risk factors of 40 cases with lower respiratory tract infection caused by stenotrophomonas maltophilia in the elderly and to investigate the drug sensitivities of Stenotrophomonas maltophilia strains. Methods Retrospective study of the clinical materials of 40 cases of lower respiratory tract infection caused by stenotrophomonas maltophilia in the elderly. The drug sensitivities against the stenotrophomonas maltophilia strains were determined by Kirby Bauer method. Results There were 30 males and 10 females. All of 40 cases had serious underlying diseases, most of which were COPD. Seventeen cases (42.5%) were mixed infections with other bacteria, most of which were P. aeruginosa, K. pneumoniae, acinetobacter calcoaceticus and candida albicans. Risk factors of infections were application of multiple antibiotics (100%), host immune suppression (70%), invasive treatment history (30%), and prolonged hospitalization. The average hospital staying time was 41.7 days. No specific clinical manifestations and chest X ray appearance were revealed. The antimicrobial tests in vitro showed that these strains were multiresistant to antibiotics, but TMP SMZ, ciprofloxacin, levofloxacin, amikacin, gentamicin and ofloxacin were sensitive. Conclusions Lower respiratory tract infection caused by Stenotrophomonas maltophilia in the elderly were commonly seen in patients who suffered from various underlying diseases, immunodeficiency, and longtime antibiotic overuse. Clinical isolates are highly resistant to most of antimicrobial agents. The diagnosis should be made according to bacteriologic examination. Antibiotics therapy is recommanded according to antimicrobial sensitivity test.
