Chronic Myelogenous Leukemia with a Variant Philadelphia Translocation: t(11;22)(q25;q11.2).
10.3343/kjlm.2006.26.4.246
- Author:
Han Sung KIM
1
;
Hyoun Chan CHO
;
Sun Hee KIM
;
Yeonsook MOON
;
Chung Hyun NAHM
;
Jong Weon CHOI
;
Jin Ju KIM
Author Information
1. Department of Laboratory Medicine, Hallym University College of Medicine, Anyang, Korea.
- Publication Type:Case Report
- Keywords:
Variant Philadelphia;
t(11;
22)(q25;
q11.2);
Chronic myelogenous leukemia
- MeSH:
Fluorescence;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*;
Reverse Transcriptase Polymerase Chain Reaction
- From:The Korean Journal of Laboratory Medicine
2006;26(4):246-248
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of chronic myelogenous leukemia displaying a variant Philadelphia translocation t(11;22)(q25;q11.2). Breakpoint 11q25 has not previously been reported. Reverse transcriptase polymerase chain reaction and fluorescence in-situ hybridization demonstrated the BCR/ABL rearrangement.