Development in radiotherapy for locally advanced non-small cell lung cancer
- VernacularTitle:局部晚期非小细胞肺癌的放射治疗
- Author:
Guoliang JIANG
;
- Publication Type:Journal Article
- Keywords:
non small cell lung cancer;
radiotherapy;
chemotherapy
- From:
China Oncology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
This article reviewed the latest developments in radiotherapy for locally advanced non small cell lung carcinomas (LANSCLC) in the past three years. ①Induction therapy before surgery, which includes chemotherapy and chemo radiotherapy. ②Chemo radiotherapy for resectable LANSCLC. It is suggested that chemo radiotherapy would be one of the choices, besides surgery. ③Chemo radiotherapy for unresectable LANSCLC. Chemotherapy is emphasized to play an important role for these patients. The models of combination of chemotherapy and irradiation are also discussed, and so are the efficacy, toxicity and tolerance. ④Three dimensional conformal radiotherapy (3DCRT). It has been demonstrated that 3DCRT could protect normal lung well, which surrounds the tumor. Therefore, irradiation dose could be increased, and local control as well as survival would be improved by this way. ⑤Unconventional fractionated irradiation. Accelerated hyperfractionated radiation therapy, which shortens the total treatment time and still remains a high dose, has resulted in good outcome. Therefore, there is a room for further studies. ⑥Application of radioprotector in lung irradiation. Amifostine has been tried and shown to have protection for normal tissues, especially in decreasing the incidences of radiation induced esophagitis and pneumonitis.
