Study on the inhibition of allogeneic transplantation rejection by the B7 antisense peptide
- VernacularTitle:B7反义肽抑制同种异基因移植排斥反应的研究
- Author:
Jin CHEN
;
Sidong XIONG
;
Ruihua ZHANG
;
Al ET
- Publication Type:Journal Article
- Keywords:
Antisense peptide;
CD28;
B7;
Allogeneic transplantation
- From:
Chinese Journal of Immunology
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
95%,WT= 1 271 6 .Lymphoproliferation reaction of the splenocytes derived from BALB/C mice was inhibited by stimulating with the antisense peptide pre treatment of allogeneic splenic cells and cardiac cells of C57 mice.The inhibition rates up to 38 4% and 36 6%.Pre treatment of allogeneic cardiac grafts resulted in prolonging the survival of cardiac transplantation 5 4 days more than the control group(n=6,P
