Study of apoptosis mechanism of the carcinoma of urinary bladder BIU-87 cell strain induced by SEA
- VernacularTitle:SEA诱导人膀胱癌BIU-87细胞凋亡机制的研究
- Author:
Yanhui LI
;
Ping LUO
;
Liqun SUN
;
Al ET
- Publication Type:Journal Article
- Keywords:
Apoptosis;
Bladder carcinoma;
SEA;
Cytometry
- From:
Chinese Journal of Immunology
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Observing the mechanism of apoptosis in the carcinoma of urinary bladder BIU 87 cell strain induced by staphylococcus enterotoxin A (SEA).Methods:The multiplicative inhibitory rate of the BIU 87 cell strain and cell cycle affected by SEA was tested with MTT colorimetry and low cytometry.Results:SEA restrain obviously the BIU 87 cell strain and have dosage dependence and obstruct the cell multiplication processes from G 1 period to S period.A crowd of cells was seen G 1 period.Conclusion:SEA having effect of cytotoxicity can make BIU 87 cell strain apoptosis and prevent the metastsis of the carcinoma of urinary bladder by pouring it into bladder.
