Adaptation of ovarian cancer cell line SKOV-3ipl cells to hypoxia and its correlation with VEGF and Bcl-2 protein expressions
- VernacularTitle:卵巢癌细胞株SKOV-3ipl对缺氧的适应及其与VEGF、Bcl-2蛋白表达的关系
- Author:
Yaping ZHU
;
Youjie FENG
;
Huimin LI
;
Al ET
- Publication Type:Journal Article
- Keywords:
ovary malignancy;
hypoxia;
Bcl 2 protein;
VEGF;
apoptosis
- From:China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To investigate the adaptation of ovarian cancer cell line SKOV 3ipl cells to hypoxia and its correlation with the expressions of VEGF and Bcl 2 protein.Methods:The monolayer SKOV 3ipl cells plated in culture bottles were placed in an anaerobic system consisting of 85%N 2, 5%CO 2, 10%H 2 with very low oxygen concentration (
