Expression of NF-?B, c-myc and ICAM-1 in colorectal cancer and its relation to the indices in clinical pathology
- VernacularTitle:核因子-?B及其相关调控基因的表达与大肠癌临床病理指标的关系
- Author:
Bin WU
;
Yuanzheng WANG
;
Renzhi WEI
;
Al ET
- Publication Type:Journal Article
- Keywords:
colorectal neoplasm;
nuclear factor ?B;
c myc;
intercellular adhesion molecule 1
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To investigate the expression of nuclear factor kappa binding (NF ?Bp65),c myc and intercellular adhesion molecule 1(ICAM 1) in colorectal cancer and its relation to clinicopathology.Methods:50 colorectal cancer patients who underwent radical surgery were studied, the expression of NF ?Bp65, c myc and ICAM 1 in them were examined by immunohistochemical method.Results:①In normal colon there was weak expression of NF ?Bp65, no expression of c myc and ICAM 1, NF kBp65,C myc and ICAM 1 were strongly expressed in colorectal cancer than in normal colon( P
