Monitoring of tissue polypeptide specific antigen in the treatment for advanced cancers and its significance
- VernacularTitle:组织多肽特异性抗原检测在中晚期肿瘤治疗中的意义
- Author:
Yehua SHEN
;
Zheng CHEN
;
Mingzhi SONG
;
- Publication Type:Journal Article
- Keywords:
tissue polypeptide specific antigen;
tumors;
therapy
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To determine the impact of serum tissue polypeptide specific antigen (TPS) in the treatment for advanced cancer patients. Methods:Serum TPS was examined in 60 advanced cancer cases. 42 of the patients received hepatic arterial chemoembolization or chemotherapy. For those with tumors derived from digestive system, TPS monitoring was performed in serial during the therapeutic courses. Results:No significant differentiation was observed in terms of age, gender, disease or tumor stage. Patients with initial TPS lower than 300 U/L had the most favorable response rate to treatment (PR,CR or MR) of 52.94%, while those with initial TPS higher than 1000 U/L showed no evidence of remission after therapy. 55.56% of the latter developed into PD ( P
