Physical and mechanical characteristic of bone cement mixed with antibiotics
- VernacularTitle:抗生素骨水泥物理和力学性能及洗提特性的实验研究
- Author:
Wei-Min FAN
;
Xi CHEN
;
Xiang LI
;
- Publication Type:Journal Article
- Keywords:
Joint prosthesis;
bone cements;
Antibiotics;
Infection
- From:
Chinese Journal of Orthopaedics
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the physical and mechanical properties of home-made bone cement mixed with different antibiotics.Methods The specimens of bone cement each of 40g were divid-ed in to6groups depending on mixed antibiotics,groupⅠmixed with1g gentamicin,groupⅡwith2g gen tam icin,groupⅢwith1g cephradine,groupⅣwith1.5g cefuroxine,groupⅤwith1g ceftriaxone and groupⅥwith out any antibiotics served as control.The dough time,compressing depth,compressive strength,bending strength and bending elastic modulus were measured respectively,elution examination of antibiotics from bone ce ment was performed by chromatography.Results The dough time and compress-ing depth of the groups were better than that of ISO5833standard,and there was no significant difference a-mong the groups.The com pressive strength and bending strength of the groupⅡwere lower than that ISO5833standard,but there was no significant difference among the groups by analysis of variance.The bending elastic modulus of the groupⅡwas lower than the control group and other groups(P
