The effect of glococorticoid in treatment of class IV lupus nephritis
- VernacularTitle:糖皮质激素对弥漫增生型狼疮性肾炎血清TGF-?_1的影响
- Author:
Ping LUO
;
Yanhui LI
;
Hua GU
;
Al ET
- Publication Type:Journal Article
- Keywords:
Glucocorticoid;
Lupus nephritis;
TGF ? 1
- From:
Chinese Journal of Immunology
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of glucocorticoid on treating class IV lupus nephritis(LN) by comparing the content of serum transforming growth factor beta(TGF ? 1).Methods:The study consisted of 33 objects,15 health controls as well as 18 cases of IV LN.The level of serum TGF ? 1 was analyzed by ELISA.Results:The level of serum TGF ? 1 was greatly reduced after the patients were treated with glucorcorticoid.Conclusion:Timely and sufficient glucocorticoid may prevent IV LN from developing into glomerulosclerosis.
