Study on association premature ventricular contraction and myocardium injury with microvascular leakage in contrasted aided echocardiography
- VernacularTitle:经静脉心肌声学造影与心肌损伤及室性期前收缩关系的研究
- Author:
Peng LI
;
Xingui GUO
;
Qing PAN
;
Al ET
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Contrast media;
Myocardial diseases;
Ventricular premature complexes
- From:Chinese Journal of Ultrasonography
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To examine the relationship between premature ventricular contraction(PVC) and microvascular leakage in the myocardium due to microvascular contrast echocardiography(MCE). Methods Thirty eight rats were randomized into 5 groups: control, ultrasound exposure only, contrast agent only, real time MCE and trigger imaging MCE. Anesthetized rats with tail vein catheter were imaged in a 37℃ water bath at left ventricular parasternal short axis view. Optison was injected at a dosage of 5 ml/kg. Frequency was 1.7 MHz, MI= 1.7 and the depth of image at 10 cm. Results PVC was detected in all ultrasound exposure groups, together with petechial hemorrhages and Evans Blue leakage in the scan band. The triggered imaging showed worse effects than real time imaging. No PVC or microvascular leakage was noticed in controls or sham exposed rats. Conclusions Induction of PVC during contrast added echocardiography is associated with microvascular leakage.
