Effect of Human Growth Hormone on Diamine Oxidase and Endotoxemia in Systemic Inflammatory Response Syndrome
- VernacularTitle:生长激素应用于全身炎症反应综合征时二胺氧化酶及内毒素变化的临床意义
- Author:
Chen WANG
;
Tong WANG
;
Xusheng LI
;
- Publication Type:Journal Article
- Keywords:
Human growth hormone Systemic inflammatory response syndrome Diamine oxidase Endotoxin Intestinal mucosa barrier
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of diamine oxidase(DAO) and endotoxin(ET) during the treatment of systemic inflammatory response syndrome with human growth hormone and the relationship between human growth hormone and intestinal mucosal barrier injury. Methods One hundred and forty six patients with systemic inflammatory response syndrome were randomly divided into operative group and non operative group, which were again randomly divided into the study group and control group.Plasma concentration of DAO and ET were determined before the treatment and 1 week after the treatment.Results Plasma concentration of DAO and ET in study group decreased after treatment with significant difference ( P