Malignant tumor following renal transplantation
- VernacularTitle:肾移植术后并发恶性肿瘤的临床分析
- Author:
Rongxi LIN
;
Shunliang YANG
;
Weizhen WU
;
Al ET
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Neoplasms;
Meta analysis
- From:
Chinese Journal of Organ Transplantation
1996;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the occurrence of malignant tumor following renal transplantation and investigate the measures of prevention and treatment.Methods The clinical data of 1 037 cases of renal transplantation in our centre between Dec. 1979 and May 2001 were retrospectively. Results Of the 1 037 cases of renal transplantation, 15 cases were diagnosed as having malignant tumor with the incidence being 1.4% . The most common types of tumor were liver cancer (6/15), followed by Kaposi's sarcoma (4/15), pulmonary cancer (2/15). The main treatments included surgical resection, reducing the dosage of immunosuppressants, radiotherapy and chemotherapy.Conclusion There is higher incidence of malignance in the renal transplantation recipient than general crowd. The effect of treatment depended on early diagnosis of cancer and early surgical operation. At the same time, the dosage of immunosuppressants was reduced to maintain normal function of the graft.
