Analysis of urologic malignant tumor in renal allograft recipients
- VernacularTitle:肾移植患者并发泌尿系统恶性肿瘤
- Author:
Meisheng ZHOU
;
Zhilian MIN
;
Youhua ZHU
;
Al ET
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Urogenital system;
Neoplasms
- From:
Chinese Journal of Organ Transplantation
1996;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the epidemiographic features of urologic malignant tumor in renal allograft recipients in a single center.Methods A retrograde analysis was undertaken on 2 300 patients who received renal allografts between June 1978 and December 2001 and anti rejection treatment for at least 3 months. Results Among 2 300 recipients, 27 were diagnosed as malignant tumors that included 9 (an incidence about 0.39% ) cases of urologic malignant tumors that were one third of 27 cases: 1 case of renal cell carcinoma, 2 cases of bilateral pelvic transitional cell carcinoma (TCC), 3 cases of unilateral pelvic TCC, 1 case of ureter TCC and 2 cases of bladder TCC. The mean age at diagnosis of urologic carcinoma was 57.5 ? 5.6 , and the mean duration of immunosuppressive treatment 58?18 months. Six cases received CsA+Aza+Pred, 3 cases CsA+MMF+Pred. Surgical treatment was carried out in 8 cases. Seven of them were alive well. One case died of the malignant tumor soon after the diagnosis. One case died of cerebral hemorrhage.Conclusion Urologic malignant tumor is an important complication in renal transplantation in our center. The occurrence of malignant tumor is intimately related to immunosuppressive treatment. We must pay more attention on painless eyeable hematuria in posttransplantation patients.
