A Prospective Comparison of Sulfate Free Polyethylene Glycol versus Sodium Phosphate Solution for Precolonoscopic Bowel Preparation.
- Author:
Jin Gook HUH
1
;
You Sun KIM
;
Jong Hyeok PARK
;
Kyung Sun OK
;
Won Cheol JANG
;
Tae Yeob JEONG
;
Soo Hyung RYU
;
Jung Hwan LEE
;
Jeong Seop MOON
Author Information
1. Department of Internal Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea. yousunk69@korea.com
- Publication Type:Original Article
- Keywords:
Sulfate free polyethylene glycol;
Sodium phosphate;
Bowel cleansing;
Patient's compliance
- MeSH:
Colonoscopy;
Compliance;
Humans;
Patient Compliance;
Phosphates;
Polyethylene;
Polyethylene Glycols;
Prospective Studies;
Sodium;
Sulfates;
Surveys and Questionnaires
- From:Korean Journal of Gastrointestinal Endoscopy
2009;39(5):265-270
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Polyethylene glycol (PEG) solution is commonly used for precolonoscopic preparation because of its safety and effectiveness. Sulfate free PEG (SF-PEG) solution was developed to reduce the salty taste by removing the sodium sulfate. The aim of this study was to compare the efficacy and patient compliance of SF-PEG and sodium phosphate (NaP) solutions for preparing the bowel before colonoscopy. METHODS: From February through April in 2007, 534 patients who underwent colonoscopy were prospectively enrolled. The efficacy of bowel cleansing was assessed by a doctor's questionnaire and the patient's compliance was assessed by a patient's questionnaire. RESULTS: There was no significant difference between the groups for the "stools and fluids" assessment of bowel cleansing (2.07 vs. 2.14, respectively, p=0.149). However, SF-PEG was more effective on the "air bubbles" assessment (1.34 vs. 1.71, respectively, p<0.001) and the overall assessment (0.72 vs. 0.91, respectively, p=0.010) than NaP. The patients preferred SF-PEG rather than NaP for "Taste" (1.34 vs. 2.25, respectively, p=0.148). However, the patients significantly preferred NaP rather than SF-PEG for "Quantity" (2.46 vs. 1.18, respectively, p<0.001). CONCLUSIONS: The SF-PEG solution showed more effectiveness for bowel cleansing as compared to the NaP solution. SF-PEG tastes better than NaP, but patients are still required to consume 4 liters for the standard preparing regimen.
