p62 antigenic analysis with IgG class of autoantibody from patients with cancers
- VernacularTitle:采用恶性肿瘤患者IgG类自身抗体研究p62的抗原性
- Author:
Sanying WANG
;
Qizhou LIAN
;
Yajun WU
;
- Publication Type:Journal Article
- Keywords:
Tumor;
p62;
Antigen associated tumor;
ELISA
- From:
Chinese Journal of Immunology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
anti p62 2 in patients with cancers All of them were lower than that of autoantibody against full length p62 The frequency of autoantibody to full length p62 was significantly higher than that of anti p62 2 and anti p62 3, but no difference with anti p62 1 Totally positive rates of autoantibody against the three fragments were lower than those of full length p62 in patients with hepatocellular cancer, gastric cancer, colorectal cancer, esophagus cancer and breast cancer but with lung cancer Conclusion:Antigenic sites in p62 were mainly located in p62 1 and the integrity of p62 structure is important for antigenic expression
