The Clinical Study of PCNA and AgNORs in Colorectal Carcinoma and Carcinoma Adjacent Mucosa
- VernacularTitle:大肠癌组织及其癌旁粘膜PCNA和AgNORs的检测及其临床意义
- Author:
Yujun HE
;
Shuangwu HE
;
Quan GAN
;
- Publication Type:Journal Article
- Keywords:
Colorectal carcinoma Proliferating cell nuclear antigen Argyrophilia nucleolar organizer regions
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression and significance of proliferating cell nuclear antigen (PCNA) and argyrophilia nucleolar organizer regions (AgNORs) in colorectal carcinoma (CRC) and carcinoma adjacent mucosa (CAM).Methods The expression of PCNA in 48 cases of colorectal carcinoma tissue, CAM and 10 cases of normal mucosa was detected by immunohistochemistry techniques. AgNORs was determined with argyrophilia stain. Results The PCNA labeling index (PCNA LI) and AgNORs count in CRC were higher than that in CAM and normal mucosa( P
