T lymphocyte activation associated membrane molecule expression in peripheral blood of patients with non-small-cell lung cancer and its clinical significance
- VernacularTitle:T细胞活化相关膜分子在非小细胞肺癌外周血中的表达及其临床意义
- Author:
Qingyong CHEN
;
Jianying ZHOU
;
Yanyi WANG
;
Al ET
- Publication Type:Journal Article
- Keywords:
non small cell lung cancer;
T lymphocyte activation associated membrane molecule;
flow cytometry
- From:
China Oncology
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To study the expression of T lymphocyte activation associated membrane molecule in peripheral blood of patients with non small cell lung cancer and study the changes in its immunity function.Methods:The lymphocyte from the peripheral blood in patients with non small cell lung cancer were immunologically double fluorescent labeled by CD3 PE and CD25/ HLA DR/ CD69 FITC were determined by flow cytometry. 25 normal donors served as controls.Results:Peripheral blood CD3 + /CD25 + ,CD3 + /HLA DR + and CD3 + /CD69 + in T lymphocyte with lung cancer were significantly lower than those in normal controls ( P
