Clinical significance of vascular endothelial growth factor and p53 gene expression in human gastric cancer
- VernacularTitle:血管内皮生长因子和抑癌基因p53在胃癌中的表达及其临床意义
- Author:
Ye ZHOU
;
Weiqi ZHU
;
Yingqiang SHI
;
Al ET
- Publication Type:Journal Article
- Keywords:
gastric cancer;
vascular endothelial growth factor;
p53 gene;
clinicopathological characteristics;
prognosis
- From:
China Oncology
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To investigate the association between the expression of vascular endothelial growth factor (VEGF) and p53, and their influence on clinicopathological characteristics and prognostic value in gastric cancer.Methods:A total of 108 paraffin embedded gastric cancer tissues were stained with the monoclonal antibodies VEGF and P53 protein by immunohistochemistry.Results:VEGF and P53 expression were observed in 53.7% and 57.4% of gastric tumors, respectively. A significant correlation was found between VEGF and p53 status ( P
