Recent advances in Eph receptors and Ephrin ligands
- VernacularTitle:Eph受体和Ephrin配体的研究进展
- Author:
Chao LUO
;
Gang TIAN
;
Minhui XU
;
- Publication Type:Journal Article
- Keywords:
receptor tyrosine kinase;
axon guidance;
angiogenesis
- From:
China Oncology
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Protein tyrosine kinase genes are the largest family of oncogenes. This is not surprising since protein tyrosine kinases are important components of signal transduction pathways that control cell shapes, proliferation, differentiation, and migration. This review will address the recent progress in understanding the function of Eph receptor and ephrin ligands in normal development and how disregulation of these functions could promote tumorigenesis.